Atomoxetine (Strattera): clear facts on use, dosing, and safety

Atomoxetine, sold as Strattera, is a non-stimulant prescription medicine for attention‑deficit/hyperactivity disorder (ADHD). If stimulants didn’t work for you or caused bad side effects, atomoxetine is a common alternative. It works differently from amphetamine or methylphenidate drugs and can help with attention, focus, and impulse control over weeks.

How atomoxetine works and when you’ll notice effects

Atomoxetine blocks the reuptake of norepinephrine in the brain, which changes signaling involved in attention and behavior. Unlike stimulants, it doesn’t usually give an immediate boost. Many people see gradual improvement over 2 to 6 weeks. If there’s no benefit after about 6 to 8 weeks, talk to your prescriber about next steps.

It’s taken by mouth once or twice a day depending on your dose. You can take it with or without food, but taking it at the same times daily helps keep levels steady and makes side effects easier to spot.

Dosing basics and practical tips

Dosing depends on age and weight. For children and teens under 70 kg, doctors often start at 0.5 mg/kg/day for a few days, then increase to about 1.2 mg/kg/day. For adults and teens 70 kg or more, a common schedule is 40 mg daily at first, then 80 mg after a few days. The usual maximum is around 100 mg per day, but your doctor will pick the right limit for you.

Don’t split or crush extended‑release capsules unless your pharmacist confirms it’s okay. If you miss a dose, take it as soon as you remember that day; don’t double doses the next day. Keep a note of when you start and any changes so you can report progress or problems to your clinician.

Common side effects include upset stomach, decreased appetite, sleepiness or trouble sleeping, dry mouth, dizziness, and mild mood changes. Most fade after a few weeks. Watch for sudden worsening of mood, new suicidal thoughts (more common in children and teens), or signs of liver trouble like dark urine, yellowing skin, or persistent nausea — call your doctor right away if those occur.

Atomoxetine can raise heart rate and blood pressure. If you have heart disease, high blood pressure, or a family history of sudden cardiac death, mention this before starting. Also check drug interactions: strong CYP2D6 inhibitors such as fluoxetine or paroxetine can raise atomoxetine levels and may need dose changes or extra monitoring.

Thinking of buying atomoxetine online? Only use pharmacies that require a valid prescription and are licensed. Avoid websites that sell prescription drugs without asking for a prescription. If you have questions about side effects, dosing, or interactions, talk with your prescriber or pharmacist — they can tailor advice to your situation.

Atomoxetine is a good option for many people with ADHD, especially when stimulants aren’t suitable. Give it time, track how you feel, and stay in touch with your healthcare team to get the most benefit with the least risk.