Sexual Side Effects: What Medications Can Cause Them and How to Spot the Signs

When you take a medication for high blood pressure, depression, or even acid reflux, you might not think about your sex life—but sexual side effects, changes in libido, arousal, or performance caused by prescription drugs are one of the most common, yet rarely discussed, side effects out there. Millions of people experience reduced desire, trouble getting or keeping an erection, delayed orgasm, or vaginal dryness after starting a new pill, and many assume it’s just aging or stress. But it’s often the drug.

These effects aren’t random. They show up with specific types of meds. antidepressants, especially SSRIs like sertraline or fluoxetine, are the most frequent culprits, with up to 70% of users reporting some form of sexual dysfunction. blood pressure meds, like beta-blockers and diuretics, can cut blood flow to key areas, making arousal harder. Even H2 blockers, used for heartburn, can interfere with hormone pathways in rare cases. And while statins help lower cholesterol, some men report lower testosterone levels after long-term use. These aren’t side effects you can ignore—they impact relationships, self-esteem, and mental health.

What makes it worse? Doctors rarely ask about it. Patients don’t bring it up because it’s embarrassing. But if you’ve noticed a change in your sex life after starting a new drug, it’s not in your head. Track it: when did it start? Did it happen after a dose change? Did it get worse with alcohol or stress? That’s the kind of detail that helps your doctor swap out the drug for something less likely to cause trouble—like switching from an SSRI to bupropion, or replacing a beta-blocker with an ACE inhibitor. You don’t have to live with it. The right fix often just means asking the right question.

The posts below dig into real cases: how certain antibiotics affect nerve signals, why lithium can dampen desire, how anticholinergics mess with arousal, and what alternatives exist when your current meds are stealing your intimacy. You’ll find clear, no-fluff advice from people who’ve been there—and the science behind what’s really happening in your body.

Sexual Side Effects from Common Medications: What You Need to Know

Sexual Side Effects from Common Medications: What You Need to Know

Many common medications - from antidepressants to blood pressure pills - can cause sexual side effects like low desire, erectile dysfunction, or trouble orgasming. Learn which drugs are most likely to cause these issues and what you can do about them.