Reassurance from Research: Clinical Studies on Brand-to-Generic Switches
Clinical studies show most generic drugs work as well as brand-name versions, saving billions annually. But for medications with narrow therapeutic indices-like antiepileptics-switching can cause seizures or side effects. Know which drugs are safe to switch and when to ask for the brand.
Partial AUC: Advanced Bioequivalence Measurements Explained
Partial AUC is a precise pharmacokinetic tool used to assess bioequivalence in complex drug formulations where traditional metrics fail. It measures drug exposure during critical time windows to ensure safety and efficacy, especially for extended-release and abuse-deterrent generics.
Bioequivalence Explained: FDA Requirements to Prove Generic Drug Equivalence
Learn how the FDA ensures generic drugs work the same as brand-name ones through bioequivalence testing. Understand the 80-125% rule, what it really means, and why generics are safe and effective.